Growth Inhibitory Effect of Bovine Lactoferrin to Toxoplasma gondii Tachyzoites in Murine Macrophages: Tyrosine Phosphorylation in Murine Macrophages Induced by Bovine Lactoferrin.
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چکیده
منابع مشابه
Effect of Shark Liver Oil on Peritoneal Murine Macrophages in Responses to Killed-Candida albicans
Objective(s) Shark Liver Oil (SLO) is an immunomodulator. Macrophages play a key role in host defense against pathogens like fungi. Candida albicans have mechanisms to escape immune system. We determined the effect of killed-Candida on the in vitro viability of macrophages and the effect of SLO on augmentation of this potency. Materials and Methods Peritoneal macrophages were separated and c...
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Lactoferrin (LF) is a well-known multifunctional protein. In this study, we report the inhibitory potency of bovine LF (bLF) on catechol-O-methyltransferase (COMT), which catalyzes methylation of catechol substrates. We found that bLF binds to and inhibits COMT using its N-terminal region. An N-terminal peptide fragment obtained from bLF by trypsin digestion showed a higher inhibitory activity ...
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In the present paper we focused on the potential role of human lactoferrin for the intracellular replication rate of T. gondii BK tachyzoites following our earlier observation that Toxoplasma gondii was able to bind human lactoferrin but not serum transferrin. The study was performed in vitro on human CaCo-2 epithelial cells and mouse L929 fibroblasts. We found that the multiplication of the pa...
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Therapeutic activity against oral candidiasis of orally administered bovine lactoferrin (LF), a multifunctional milk protein, was shown in a previous report using an immunosuppressed murine model. In the present study, the influence of orally administered LF on immune responses relevant to this therapeutic effect was examined. Because mice were immunosuppressed with prednisolone 1 day before an...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1998
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.60.369